ED-Net Published in Biomedical Signal Processing and Control

Our paper ED-Net: A Hybrid Deep Learning Framework for Precise Polyp Segmentation Integrating EfficientNetB0 with Double U-Net Architecture and Atrous Spatial Pyramid Pooling with Test-Time Augmentation has been published in Biomedical Signal Processing and Control, Elsevier (Q1, IF: 4.9).

About the Paper

Colorectal cancer (CRC) is a major global health concern, and colorectal polyps are early indicators of CRC. ED-Net is a hybrid deep learning framework designed to address three core limitations in existing polyp segmentation models: failure to jointly optimize Dice and IoU, limited cross-dataset generalization, and poor balance between segmentation accuracy and computational efficiency for real-time clinical deployment.

Key Contributions

  • Hybrid dual-encoder-decoder combining EfficientNetB0 and Double U-Net with ASPP and SE-block channel attention
  • Test-Time Augmentation (TTA) applied at inference to improve boundary delineation without modifying the network architecture
  • Dual-mode clinical deployment strategy — real-time screening without TTA (47.17 FPS) and offline diagnostic analysis with TTA (12.93 FPS)
  • Cross-dataset validation on three external benchmarks demonstrating clinical robustness under domain shift
  • Grad-CAM and SE block attention analysis confirming clinically interpretable decision-making

Results

Dataset Accuracy Dice IoU
Kvasir-SEG (with TTA) 97.13% 92.26% 91.08%
CVC-ClinicDB 96.39% 80.62% 79.79%
ETIS-LaribPolypDB 97.57% 77.15% 80.14%
PolypGen2021 95.66% 80.71% 74.32%

Citation

R. K. Kundu, H. B. Kibria, Md. F. Ahamed, and M. E. H. Chowdhury, “ED-Net: A Hybrid Deep Learning Framework for Precise Polyp Segmentation Integrating EfficientNetB0 with Double U-Net Architecture and Atrous Spatial Pyramid Pooling with Test-Time Augmentation,” Biomedical Signal Processing and Control, vol. 123, Part A, p. 110566, Elsevier, 2026.

DOI: 10.1016/j.bspc.2026.110566